Moving beyond the Cox proportional hazards model in survival data analysis: a cervical cancer study
نویسندگان
چکیده
منابع مشابه
Gradient lasso for Cox proportional hazards model
MOTIVATION There has been an increasing interest in expressing a survival phenotype (e.g. time to cancer recurrence or death) or its distribution in terms of a subset of the expression data of a subset of genes. Due to high dimensionality of gene expression data, however, there is a serious problem of collinearity in fitting a prediction model, e.g. Cox's proportional hazards model. To avoid th...
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Let δi = 1 if the i time Yi is an observed death and δi = 0 if it was a right-censored event: That is, the individual was alive at time Yi, but was last seen at that time. If Ti (1 ≤ i ≤ n) are the true survival or failure times, then Yi = Ti if δi = 1 and Yi < Ti if δi = 0, in which case the true failure time Ti is unknown. We also assume d-dimensional covariate vectors X1, X2, . . . , Xn for ...
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Survival analysis techniques are often used in clinical and epidemiologic research to model time until event data. Using SAS® system's PROC PHREG, Cox regression can be employed to model time until event while simultaneously adjusting for influential covariates and accounting for problems such as attrition, delayed entry, and temporal biases. Furthermore, by extending the techniques for single ...
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The Cox proportional hazards regression model has been widely used in the analysis of survival/duration data. It is semiparametric because the model includes a baseline hazard function that is completely unspecified. We study here the statistical inference of the Cox model where some information about the baseline hazard function is available, but it still remains as an infinite dimensional nui...
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Some failure time data come from a population that consists of some subjects who are susceptible to and others who are nonsusceptible to the event of interest. The data typically have heavy censoring at the end of the follow-up period, and a standard survival analysis would not always be appropriate. In such situations where there is good scientific or empirical evidence of a nonsusceptible pop...
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ژورنال
عنوان ژورنال: BMJ Open
سال: 2020
ISSN: 2044-6055,2044-6055
DOI: 10.1136/bmjopen-2019-033965